4-Tert-butyl-2-nitrobenzoic acid → 2-Amino-4-tert-butylbenzoic acid

HRID 600356

反応式

HRID 600356 の反応式
[C:1]([C:5]1[CH:13]=[CH:12][C:8]([C:9]([OH:11])=[O:10])=[C:7]([N+:14]([O-])=O)[CH:6]=1)([CH3:4])([CH3:3])[CH3:2]>[Pd].C(O)C>[NH2:14][C:7]1[CH:6]=[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[CH:13]=[CH:12][C:8]=1[C:9]([OH:11])=[O:10]

参加物

4

反応物 1

HCID 2573264-Tert-butyl-2-nitrobenzoic acid

生成物 1

HCID 146458722-Amino-4-tert-butylbenzoic acid収率 10.3%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

4-tert-Butyl-2-nitro-benzoic acid (199 mg, 8.91 mmol), and 10% palladium on carbon (40 mg) were stirred in 6 mL ethanol under an atmosphere of hydrogen for 3 hours. The resulting mixture was filtered and concentrated in vacuo to yield 2-Amino-4-tert-butyl-benzoic acid (177 mg, 0.916 mmol).

後処理

  1. filtrationThe resulting mixture was filtered
  2. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-e422b9e77b964f47ae300cabc0da87c4
出典データセット
uspto-grants-2011_03
特許番号
US07902194B2

関連ノート

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