Water → 2-(Isoquinolin-7-yloxy)pentanoic acid sodium salt
反応式
O.[OH-].[Na+:3].[CH:4]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([O:14][CH:15]([CH2:21][CH2:22][CH3:23])[C:16]([O:18]CC)=[O:17])[CH:12]=2)[CH:7]=[CH:6][N:5]=1>CO>[Na+:3].[CH:4]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([O:14][CH:15]([CH2:21][CH2:22][CH3:23])[C:16]([O-:18])=[O:17])[CH:12]=2)[CH:7]=[CH:6][N:5]=1参加物
5
実験手順
10 ml of water and 840 mg (21.0 mmol) of sodium hydroxide are added to a solution of 5.20 g (19.0 mmol) of ethyl 2-(isoquinolin-7-yloxy) -pentanoate in 50 ml of methanol, and the mixture is stirred at room temperature for 42 hours. The solvent is removed by distillation, giving 2-(isoquinolin-7-yloxy)pentanoic acid sodium salt as a colourless solid; ESI 246.
後処理
- customThe solvent is removed by distillation
出典と根拠
- ORDレコード
- ord-cbb8d4ba22014274923d23200a4f0d41
- 出典データセット
- uspto-grants-2011_03
- 特許番号
- US07902223B2
反応ノート
読み込み中…