Butylamine → N-butyl-1,1-dimethyl-1-sila-2-azacyclopentane
反応式
[CH2:1]([NH2:5])[CH2:2][CH2:3][CH3:4].Cl[CH2:7][CH2:8][CH2:9][Si:10]([CH3:13])([CH3:12])Cl>>[CH2:1]([N:5]1[CH2:7][CH2:8][CH2:9][Si:10]1([CH3:13])[CH3:12])[CH2:2][CH2:3][CH3:4]参加物
3
反応条件
- 温度
- 10 °C
実験手順
An initial charge of 508 g (6.94 mol) of 1-butylamine is admixed dropwise over the course of 2.5 h with 171 g (1.00 mol) of chloropropyldimethylchlorosilane and the mixture is heated at reflux for 12 h. Following distillative removal of the excess 1-butylamine, the residue is diluted with 350 ml of toluene and cooled to 10° C. The precipitate it forms is filtered off and the filtrate is distilled in vacuo. This gives 134.5 g of N-butyl-1,1-dimethyl-1-sila-2-azacyclopentane.
後処理
- temperaturethe mixture is heated
- temperatureat reflux for 12 h
- customremoval of the excess 1-butylamine
- additionthe residue is diluted with 350 ml of toluene
- filtrationThe precipitate it forms is filtered off
- distillationthe filtrate is distilled in vacuo
出典と根拠
- ORDレコード
- ord-cac1f95d9a934ec6b9bb2fa21fb32c46
- 出典データセット
- uspto-grants-2011_03
- 特許番号
- US07906179B2
反応ノート
読み込み中…