3-(4-Methoxyphenyl)-4-oxo-4H-1-benzopyran-7-yl acetate → HCID 9926870、化合物

HRID 603275ノート

反応式

HRID 603275 の反応式
[C:1]([O:4][C:5]1[CH:14]=[C:13]2[C:8]([C:9](=[O:23])[C:10]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[CH:11][O:12]2)=[CH:7][CH:6]=1)(=[O:3])[CH3:2]>C(O)C.[Pd]>[C:1]([O:4][C:5]1[CH:14]=[C:13]2[C:8]([CH:9]([OH:23])[CH:10]([C:15]3[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=3)[CH2:11][O:12]2)=[CH:7][CH:6]=1)(=[O:3])[CH3:2]

参加物

4

反応物 1

HCID 9088273-(4-Methoxyphenyl)-4-oxo-4H-1-benzopyran-7-yl acetate

生成物 1

HCID 9926870HCID 9926870、化合物収率 101.4%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

Palladium-on-charcoal (5%, 0.08 g) was added to a suspension of 7-acetoxy-4′-methoxyisoflavone (0.5 g, 1.6 mmol) in absolute ethanol (400 ml) and the mixture was stirred at room temperature under a hydrogen atmosphere for 55 hours. The catalyst was removed by filtration through Celite and the filtrate was evaporated in vacuo to yield 7-acetoxy-4′-methoxyisoflavan-4-ol (0.51 g, 100%) in quantitative yield. A nuclear magnetic resonance spectrum revealed the product to be a clean 1:1 mixture of cis- and trans-7-acetoxy-4′-methoxyisoflavan-4-ol.

後処理

  1. customThe catalyst was removed by filtration through Celite
  2. customthe filtrate was evaporated in vacuo

出典と根拠

ORDレコード
ord-ae4581d882744155a243e4fa46ad46ea
出典データセット
uspto-grants-2011_03
特許番号
US07906660B2

反応ノート

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