8-(4-Methoxyphenyl)-1,4-dioxaspiro[4.5]dec-7-ene → HCID 67057737、化合物

HRID 604667ノート

反応式

HRID 604667 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH2:18][CH2:17][C:12]3([O:16][CH2:15][CH2:14][O:13]3)[CH2:11][CH:10]=2)=[CH:5][CH:4]=1>CCO.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:18][CH2:17][C:12]3([O:16][CH2:15][CH2:14][O:13]3)[CH2:11][CH2:10]2)=[CH:5][CH:4]=1

参加物

4

反応物 1

HCID 148634918-(4-Methoxyphenyl)-1,4-dioxaspiro[4.5]dec-7-ene

生成物 1

HCID 67057737HCID 67057737、化合物

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

To a solution of 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]dec-7-ene (526.8 mg, 2.14 mmoL) in EtOH (20 mL) was added 10% Pd/C (50 mg). The reaction was put under an atmosphere of H2 (balloon) and stirred vigorously at room temperature. After 1.5 hours, the catalyst was removed by filtration. The filtrate was concentrated to afford 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane. 1H NMR (500 MHz, CDCl3): δ 7.14-7.17 (m, 2H), 6.82-6.85 (m, 2H), 3.98 (s, 4H), 3.79 (s, 3H), 2.52 (m, 1H), 1.64-1.86 (m, 8H).

後処理

  1. customthe catalyst was removed by filtration
  2. concentrationThe filtrate was concentrated

出典と根拠

ORDレコード
ord-f9e80bc20e31475ab37f48e1c6ff31e8
出典データセット
uspto-grants-2011_03
特許番号
US07910592B2

反応ノート

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