Ammonium Chloride → HCID 67040258、化合物
反応式
[Cl:1][C:2]([Cl:33])([Cl:32])[CH2:3][O:4][C:5](=[O:31])[NH:6][C:7]1[CH:12]=[CH:11][C:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([C:20](=[O:27])[NH:21][C:22]3[S:23][CH:24]=[N:25][N:26]=3)=[CH:16][C:15]=2[N+:28]([O-])=O)=[CH:9][CH:8]=1.[NH4+].[Cl-]>[Fe]>[Cl:32][C:2]([Cl:1])([Cl:33])[CH2:3][O:4][C:5](=[O:31])[NH:6][C:7]1[CH:8]=[CH:9][C:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([C:20](=[O:27])[NH:21][C:22]3[S:23][CH:24]=[N:25][N:26]=3)=[CH:16][C:15]=2[NH2:28])=[CH:11][CH:12]=1参加物
4
実験手順
The product of Example 166A (340 mg, 0.6197 mmol) was reduced with Fe and NH4Cl following the procedure in Example 9E to yield the title compound (231 mg, 72% yield) as a white solid. 1H NMR (300 MHz, DMSO-D6) δ ppm: 4.94 (s, 2 H) 5.59 (s, 2 H) 7.14-7.35 (m, 4 H) 7.42 (s, 1 H) 7.50 (d, J=8.46 Hz, 2 H) 9.22 (s, 1 H) 10.26 (s, 1 H); MS (ESI) m/z 520 (M+H)+.