Hydrogen Bromide → HCID 67040294、化合物
反応式
C(OC(=O)[NH:10][C:11]1[CH:12]=[N:13][CH:14]=[C:15]([Br:17])[CH:16]=1)C1C=CC=CC=1.[BrH:19]>>[BrH:17].[BrH:19].[Br:17][C:15]1[CH:16]=[C:11]([NH2:10])[CH:12]=[N:13][CH:14]=1参加物
3
実験手順
A suspension of the product of Example 231A (200 mg, 0.6512 mmol) in a hydrogen bromide solution (33 weight % HBr in acetic acid, 3 mL) was stirred at room temperature for 4 hours. The solvent was removed by rotary evaporation in vacuo and the residue azeotroped with dry toluene (10 mL) to afford the title compound as a light peach colored solid (205 mg, 94%).
後処理
- customThe solvent was removed by rotary evaporation in vacuo
- customthe residue azeotroped with dry toluene (10 mL)
出典と根拠
- ORDレコード
- ord-e35fcc59c6924741908b16688acbbb6c
- 出典データセット
- uspto-grants-2011_03
- 特許番号
- US07910595B2
反応ノート
読み込み中…