Anthranilic Acid → Acetanthranil

HRID 610472

反応式

HRID 610472 の反応式
[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[NH2:4].[C:11](OC(=O)C)(=O)[CH3:12]>>[CH3:11][C:12]1[O:9][C:1](=[O:10])[C:2]2[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=2[N:4]=1

参加物

3

反応物 2

HCID 227Anthranilic AcidHCID 7918Acetic Anhydride

生成物 1

HCID 68236Acetanthranil

実験手順

Anthranilic acid (274.3 g) and acetic anhydride (1.1 L) were combined then heated at reflux for 3.5 hours. The reaction mixture was concentrated under vacuum. The residue was combined with methanol (550 mL) then concentrated under vacuum to provide 2-methyl-4-oxo-3,1-benzoxazine as a brown oil.

後処理

  1. temperatureat reflux for 3.5 hours
  2. concentrationThe reaction mixture was concentrated under vacuum
  3. concentrationthen concentrated under vacuum

出典と根拠

ORDレコード
ord-ffac392fa140465e953adccd91308e75
出典データセット
uspto-grants-1999_12
特許番号
US05998619

関連ノート

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