Hydrochloric Acid → 2-Methoxy-6-methylbenzoic acid

HRID 611703

反応式

HRID 611703 の反応式
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:4]=1[C:5]([O:7]CC)=[O:6].CO.[OH-].[Na+].Cl>O>[CH3:1][O:2][C:3]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:4]=1[C:5]([OH:7])=[O:6]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 14798Sodium HydroxideHCID 5910602-Methoxy-6-methyl-benzoic acid ethyl ester

生成物 1

HCID 2731702-Methoxy-6-methylbenzoic acid

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

A mixture of ethyl 2-methoxy-6-methylbenzoate (5.0 g, 25 mmol), water (10 ml), methanol (40 ml) and sodium hydroxide (2.1 g, 50 mmol) is heated under reflux with stirring. The reaction mixture is diluted with water (150 ml) and acidified with concentrated hydrochloric acid. The solid material is collected by filtration, washed with water and dried yielding dark yellow crystals, 2.1 g, mp 136° C.

後処理

  1. temperatureis heated
  2. temperatureunder reflux
  3. filtrationThe solid material is collected by filtration
  4. washwashed with water
  5. customdried
  6. customyielding dark yellow crystals, 2.1 g, mp 136° C.

出典と根拠

ORDレコード
ord-c7f8dbd0b57f4d3ea9efe6be3a909883
出典データセット
uspto-grants-1999_12
特許番号
US06001883

関連ノート

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