Water → 5-Fluoro-3-methyl-2-nitrobenzoic acid
反応式
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([CH3:11])[CH:10]=1)[C:5]([OH:7])=[O:6].[N+:12]([O-])([O-:14])=[O:13].[K+].O>OS(O)(=O)=O>[F:1][C:2]1[CH:10]=[C:9]([CH3:11])[C:8]([N+:12]([O-:14])=[O:13])=[C:4]([CH:3]=1)[C:5]([OH:7])=[O:6]参加物
5
実験手順
3-Fluoro-5-methylbenzoic acid (4 g, 25.96 mmol) and KNO3 (2.884 g, 28.556 mmol) were dissolved in conc. H2SO4 (32 mL) at 0° C. The mixture was stirred at rt for 1 h. Water (60 mL) was added, and the resulting precipitate was filtered and dried to provide the title compound, which was used without further purification.
後処理
- filtrationthe resulting precipitate was filtered
- customdried
出典と根拠
- ORDレコード
- ord-4d41f93c6fe541ed878f729d252ca1c6
- 出典データセット
- uspto-grants-2016_09
- 特許番号
- US09440982B2
反応ノート
読み込み中…