Water → HCID 10499321、化合物

HRID 613017ノート

反応式

HRID 613017 の反応式
Cl[C:2]1[CH:7]=[C:6]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:21][CH3:22])=[C:15]([O:18][CH2:19][CH3:20])[CH:16]=3)[CH:11]=[C:10]([CH2:23][OH:24])[C:9]=2[CH2:25][OH:26])[CH:5]=[CH:4][N:3]=1.O.O.[NH2:29][NH2:30]>>[NH:29]([C:2]1[CH:7]=[C:6]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:21][CH3:22])=[C:15]([O:18][CH2:19][CH3:20])[CH:16]=3)[CH:11]=[C:10]([CH2:23][OH:24])[C:9]=2[CH2:25][OH:26])[CH:5]=[CH:4][N:3]=1)[NH2:30]

参加物

4

反応物 3

HCID 962WaterHCID 24654Hydrazine hydrate (1:1)HCID 10738129HCID 10738129、化合物

生成物 1

HCID 10499321HCID 10499321、化合物

実験手順

A suspension of 1-(2-chloro-4-pyridyl)-2,3-bis(hydroxymethyl)-6-methoxy-7-ethoxynaphthalene (16.0 g) in hydrazine hydrate (50 ml) is refluxed for four hours. The mixture is cooled to room temperature, and then thereto is added water. The precipitated crystals are collected by filtration, washed with water, and dried to give 1-(2-hydrazino-4-pyridyl)-2,3-bis(hydroxymethyl)-6-methoxy-7-ethoxynaphthalene (14.5 g).

後処理

  1. temperatureis refluxed for four hours
  2. filtrationThe precipitated crystals are collected by filtration
  3. washwashed with water
  4. customdried

出典と根拠

ORDレコード
ord-96d05e891c3f4fa4bc20fbd18cc4dea9
出典データセット
uspto-grants-1999_12
特許番号
US06005106

反応ノート

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