Water → 2-Methyl-3-hydroxy-4-mercaptomethyl-5-vinylpyridine
反応式
O.O.O.O.O.[S:6]([O-])([O-])(=O)=S.[Na+].[Na+].O.Cl.[CH3:15][C:16]1[C:21]([OH:22])=[C:20]([CH2:23]Cl)[C:19]([CH:25]=[CH2:26])=[CH:18][N:17]=1>C(O)C>[CH3:15][C:16]1[C:21]([OH:22])=[C:20]([CH2:23][SH:6])[C:19]([CH:25]=[CH2:26])=[CH:18][N:17]=1参加物
5
反応条件
- 温度
- 75 °C
実験手順
A solution of 20 g. of sodium thiosulfate pentahydrate in 15 ml. of water is added to a solution of 18 g. of 2-methyl-3-hydroxy-4-chloromethyl-5-vinylpyridine hydrochloride in 100 ml. of 50% ethanol. The mixture is heated one hour at 75° C., cooled and evaporated to dryness to give Bunte salt of 2-methyl-3-hydroxy-4-mercaptomethyl-5-vinylpyridine, m.p. 198°-200° C.
後処理
- temperaturecooled
- customevaporated to dryness
出典と根拠
- ORDレコード
- ord-5f18b1df2bc04322a520859ea822062d
- 出典データセット
- uspto-grants-1979_03
- 特許番号
- US04144342
反応ノート
読み込み中…