Hydrochloric Acid → 2-Dibenzothiophenecarboxylic acid

HRID 614494ノート

反応式

HRID 614494 の反応式
[C:1]([C:4]1[CH:16]=[CH:15][C:7]2[S:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:6]=2[CH:5]=1)(=[O:3])C.Cl[O-:18].[Na+].[OH-].[Na+].Cl>O1CCOCC1>[CH:5]1[C:6]2[C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=3[S:8][C:7]=2[CH:15]=[CH:16][C:4]=1[C:1]([OH:3])=[O:18]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 3120271-(Dibenzo[b,d]thiophen-2-yl)ethan-1-oneHCID 23665760Sodium Hypochlorite

生成物 1

HCID 32900242-Dibenzothiophenecarboxylic acid

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

2-Acetyldibenzothiophene (2.24 g.), sodium hypochlorite solution, (47 ml. containing 5.7% available chlorine), Normal sodium hydroxide solution (50 ml.) and dioxan (50 ml.), were heated on a steam bath with stirring for 5 hr. The mixture was acidified with excess hydrochloric acid, and the precipitated colourless solid filtered off, washed with water, and recrystallise twice from acetic acid to give dibenzothiophene-2-carboxylic acid, m.pt. 281°-283° C.

後処理

  1. filtrationthe precipitated colourless solid filtered off
  2. washwashed with water
  3. customrecrystallise twice from acetic acid

出典と根拠

ORDレコード
ord-29baabac2af24bcfb90c954f04a45a2d
出典データセット
uspto-grants-1979_03
特許番号
US04145350

反応ノート

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