Hydrochloric Acid → Norfloxacin hydrochloride

HRID 614907

反応式

HRID 614907 の反応式
O.O.O.O.O.[CH2:6]([N:8]1[C:17]2[C:12](=[CH:13][C:14]([F:24])=[C:15]([N:18]3[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]3)[CH:16]=2)[C:11](=[O:25])[C:10]([C:26]([OH:28])=[O:27])=[CH:9]1)[CH3:7].C(N1C2C(=CC(F)=C(N3CCNCC3)C=2)C(=O)C(C(O)=O)=C1)C.[ClH:52]>C(O)C>[ClH:52].[CH2:6]([N:8]1[C:17]2[C:12](=[CH:13][C:14]([F:24])=[C:15]([N:18]3[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]3)[CH:16]=2)[C:11](=[O:25])[C:10]([C:26]([OH:28])=[O:27])=[CH:9]1)[CH3:7]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 4539NorfloxacinHCID 706035241-Ethyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxoquinoline-3-carboxylic acid pentahydrate

生成物 1

HCID 12733888Norfloxacin hydrochloride

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

The compound (I) or (II) was dissolved in ethanol and acidified with concentrated hydrochloric acid. The resulting precipitate was collected, washed with ethanol, and dried to give 1-ethyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxoquinoline-3-carboxylic acid hydrochloride (III) as colorless needles, m.p. above 300° C.

後処理

  1. customThe resulting precipitate was collected
  2. washwashed with ethanol
  3. customdried

出典と根拠

ORDレコード
ord-9db6c02d96a74a82888d23a4fe2324b2
出典データセット
uspto-grants-1979_03
特許番号
US04146719

関連ノート

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