Diethylamine → N,N-Diethyl-4-phenylquinazoline-2-carboxamide
反応式
[C:1]1([C:7]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[N:10]=[C:9]([C:17]([OH:19])=O)[N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)(Cl)=O.[CH2:24]([NH:26][CH2:27][CH3:28])[CH3:25]>C1(C)C=CC=CC=1>[CH2:24]([N:26]([CH2:27][CH3:28])[C:17]([C:9]1[N:8]=[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[N:10]=1)=[O:19])[CH3:25]参加物
5
実験手順
Operations are carried out as for Example 19, starting from 2.5 g of 4-phenyl quinazoline 2-carboxylic acid, 10 ml of thionyl chloride 25 ml of toluene and 25 ml of diethylamine. 1.27 g of N,N-diethyl 4-phenyl quinazoline 2-carboxamide, melting at 101° C., is obtained.
出典と根拠
- ORDレコード
- ord-3d8dc96cd02c4866829b0a57e04aca70
- 出典データセット
- uspto-grants-1985_02
- 特許番号
- US04499094
反応ノート
読み込み中…