Acetyl chloride → Methyl 3-(4-methylphenyl)-2-propenoate

HRID 615501

反応式

HRID 615501 の反応式
[CH3:1][C:2]1[CH:12]=[CH:11][C:5]([CH:6]=[CH:7][C:8]([OH:10])=[O:9])=[CH:4][CH:3]=1.[C:13](Cl)(=O)C>CO>[CH3:1][C:2]1[CH:12]=[CH:11][C:5]([CH:6]=[CH:7][C:8]([O:10][CH3:13])=[O:9])=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 6367Acetyl chlorideHCID 158353-(p-Tolyl)acrylic acid

生成物 1

HCID 589472Methyl 3-(4-methylphenyl)-2-propenoate

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A solution of 6.0 g (37.0 mmol) of 4-methylcinnamic acid in 120 ml of anhydrous MeOH was treated with 6 ml of acetyl chloride and stirred at reflux for 18 hours. Evaporation of the MeOH gave the title ester as a white solid, mp 53.5°-57.5° C.

後処理

  1. temperatureat reflux for 18 hours
  2. customEvaporation of the MeOH

出典と根拠

ORDレコード
ord-48020e780ce84bf2a68e8cb41673e567
出典データセット
uspto-grants-1985_02
特許番号
US04499299

関連ノート

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