化工社化工社 化学情報印刷レポート · 研究参考用
2-Chloroethyldiisopropylammonium chloride → 2-Propanamine, N-(2-(2-butoxyphenoxy)ethyl)-N-(1-methylethyl)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chloroethyldiisopropylammonium chloride | HCID 77942 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 反応物 | o-Butoxyphenol | HCID 12447746 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-Propanamine, N-(2-(2-butoxyphenoxy)ethyl)-N-(1-methylethyl)- | HCID 3042672 | — |
反応手順
To 750 ml of absolute ethanol was added gradually 13.8 g (0.60 mole) of metallic sodium cut into pieces. After all the sodium had reacted 49.8 g (0.30 mole) of o-butoxyphenol was added. The solution was cooled down in ice-water whereupon a solution of 60.0 g (0.30 mole) of diisopropylaminoethylchloride hydrochloride in 150 ml of absolute ethanol was added rapidly with stirring. The reaction mixture was then boiled under reflux for 5 hours.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04073917 |
| 出典データセット | uspto-grants-1978_02 |
| ORD ID | ord-e3e95e7300674abbb8792069d63bc213 |
| 出典メモ | uspto-grants-1978_02 |