2-Chloroethyldiisopropylammonium chloride → 1-n-Propoxy-2-(2'-diisopropylaminoethoxy)-benzene

HRID 616371ノート

反応式

HRID 616371 の反応式
[Na].[CH2:2]([O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[OH:12])[CH2:3][CH3:4].Cl.[CH:14]([N:17]([CH2:21][CH2:22]Cl)[CH:18]([CH3:20])[CH3:19])([CH3:16])[CH3:15]>C(O)C>[CH2:2]([O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[O:12][CH2:22][CH2:21][N:17]([CH:18]([CH3:20])[CH3:19])[CH:14]([CH3:16])[CH3:15])[CH2:3][CH3:4]

参加物

5

反応物 3

HCID 779422-Chloroethyldiisopropylammonium chlorideHCID 80476o-PropoxyphenolHCID 5360545Sodium

生成物 1

HCID 542371341-n-Propoxy-2-(2'-diisopropylaminoethoxy)-benzene

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

The compound was prepared as described in Example 1, using sodium (3.45 g; 150 mole), 0-propoxyphenol (11.4 g; 75 mmole) and diisopropylaminoethylchloride hydrochloride (15.0 g; 75 mmole) in 200 ml of ethanol. Yield 12.7 g (64%) of product, boiling at 109°-110° C under a pressure of 0.001 mm.Hg, nD25 : 1.4961. Calcd. for C17H29NO2 : C 73.07%, H 10.46%, N 5.01%. Found C 73.2% H 10.5%, N 4.96%.

後処理

  1. customThe compound was prepared

出典と根拠

ORDレコード
ord-9e3be3fd5f284445a04496fd16570d20
出典データセット
uspto-grants-1978_02
特許番号
US04073917

反応ノート

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