Dimethylamine → Ethyl 2-dimethylaminomethylacrylate
反応式
[CH2:1]=O.[C:3]([O:9][CH2:10][CH3:11])(=[O:8])[CH2:4][C:5]([O-])=O.[K+].[CH3:13][NH:14][CH3:15]>O>[CH3:13][N:14]([CH2:5][C:4](=[CH2:1])[C:3]([O:9][CH2:10][CH3:11])=[O:8])[CH3:15]参加物
5
実験手順
Formaldehyde (60 ml of 40% solution) was added to a stirred solution of potassium ethyl malonate (34g) and dimethylamine (40 ml of 26% solution) in water (100 ml) at 15° C. The solution was stirred at laboratory temperature for one hour and then boiled under reflux for one hour. After cooling the solution was extracted with ether and the ether was evaporated to leave the product as a yellow oil. This was distilled to give a clear oil (boiling point 84° C/20 mm).
後処理
- temperatureunder reflux for one hour
- temperatureAfter cooling the solution
- extractionwas extracted with ether
- customthe ether was evaporated
出典と根拠
- ORDレコード
- ord-056f3d710dee46f49a7fd54ed0f847ad
- 出典データセット
- uspto-grants-1978_02
- 特許番号
- US04074051
反応ノート
読み込み中…