p-Toluenesulfonic acid → HCID 20367290、化合物
反応式
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[CH2:4][NH:5][NH2:6].C([O:13][C:14](=O)[CH:15]=[C:16]([NH2:20])OCC)C.C1(C)C=CC(S(O)(=O)=O)=CC=1>C(O)C>[NH2:20][C:16]1[NH:6][N:5]([CH2:4][C:3]2[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=2[CH3:1])[C:14](=[O:13])[CH:15]=1参加物
5
実験手順
27.5 g of o-methylbenzylhydrazine, dissolved in 100 ml of ethanol, were added dropwise at room temperature to a solution of 32 g of β-amino-β-ethoxyacrylic acid ethyl ester and 1.5 g of p-toluenesulphonic acid in 300 ml of ethanol. After standing overnight, the reaction solution was concentrated in vacuo and the compound identified above, which separated out as a precipitate, was filtered off and recrystallised from ethanol. Melting point: 138°, 15 g (37%).
後処理
- concentrationthe reaction solution was concentrated in vacuo
- customseparated out as a precipitate
- filtrationwas filtered off
- customrecrystallised from ethanol
出典と根拠
- ORDレコード
- ord-b03a0eb3f8394fa597538476e091419f
- 出典データセット
- uspto-grants-1978_02
- 特許番号
- US04076943
反応ノート
読み込み中…