Nitric Acid → Acetamide, N-(2,4-dimethyl-5-nitrophenyl)-

HRID 618222ノート

反応式

HRID 618222 の反応式
[N+:1]([O-:4])(O)=[O:2].[CH3:5][C:6]1[CH:11]=[C:10]([CH3:12])[CH:9]=[CH:8][C:7]=1[NH:13][C:14](=[O:16])[CH3:15]>S(=O)(=O)(O)O>[CH3:5][C:6]1[CH:11]=[C:10]([CH3:12])[C:9]([N+:1]([O-:4])=[O:2])=[CH:8][C:7]=1[NH:13][C:14](=[O:16])[CH3:15]

参加物

4

反応物 2

HCID 944Nitric AcidHCID 16303N-(2,4-Dimethylphenyl)acetamide

生成物 1

HCID 112848Acetamide, N-(2,4-dimethyl-5-nitrophenyl)-

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

反応条件

温度
0 °C

実験手順

A mixture of concentrated nitric acid (20 mL) and concentrated sulfuric acid (20 mL) was cooled in an ice-salt bath to 0° C. N-(2,4-dimethylphenyl)acetamide (9.5 g) was added portionwise at such a rate to maintain the temperature below 5° C. The mixture was then allowed to stir in the cold for an additional one hour.

後処理

  1. temperatureto maintain the temperature below 5° C

出典と根拠

ORDレコード
ord-80511f65a2bb47f180d0bd088cb65e37
出典データセット
uspto-grants-1999_09
特許番号
US05952362

反応ノート

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