Methanol → Z-Gln-ome

HRID 618661

反応式

HRID 618661 の反応式
S(Cl)(Cl)(=O)=O.[CH2:6]([O:13][C:14]([NH:16][C@H:17]([C:23]([OH:25])=[O:24])[CH2:18][CH2:19][C:20](=[O:22])[NH2:21])=[O:15])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[CH3:26]O>>[CH3:26][O:24][C:23](=[O:25])[C@H:17]([CH2:18][CH2:19][C:20](=[O:22])[NH2:21])[NH:16][C:14]([O:13][CH2:6][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1)=[O:15]

参加物

4

反応物 3

HCID 887MethanolHCID 24648Sulfuryl chlorideHCID 75855L-Glutamine, N2-[(phenylmethoxy)carbonyl]-

生成物 1

HCID 7020255Z-Gln-ome

実験手順

Sulphuryl chloride (1 g) was added to a stirred mixture of N-benzyloxycarbonyl-L-glutamine (100 g) and methanol (1200 ml) and the mixture was stirred at ambient temperature for 24 hours. The mixture was evaporated to give N-benzyloxycarbonyl-L-glutamine methyl ester (105 g).

後処理

  1. customThe mixture was evaporated

出典と根拠

ORDレコード
ord-7c388e813ccc4a57ab2a1f330e68813f
出典データセット
uspto-grants-1999_09
特許番号
US05955463

関連ノート

読み込み中…