4-Hydroxybenzoic Acid → Ethenyl 4-hydroxybenzoate

HRID 619546ノート

反応式

HRID 619546 の反応式
[C:1]([O:4][CH:5]=[CH2:6])(=[O:3])[CH3:2].[OH:7][C:8]1[CH:16]=[CH:15]C(C(O)=O)=[CH:10][CH:9]=1.C([O-])(=O)C.[K+]>C([O-])(=O)C.[Pd+2].C([O-])(=O)C.ClCCl>[OH:7][C:8]1[CH:16]=[CH:15][C:2]([C:1]([O:4][CH:5]=[CH2:6])=[O:3])=[CH:10][CH:9]=1

参加物

6

反応物 3

HCID 1354-Hydroxybenzoic AcidHCID 7904Vinyl AcetateHCID 517044Potassium Acetate

生成物 1

HCID 13040874Ethenyl 4-hydroxybenzoate収率 10%

試薬・触媒・溶媒 2

HCID 167845palladium(II) acetate触媒HCID 6344Dichloromethane溶媒

実験手順

2000 g of dichloromethane, 24.9 g of vinyl acetate, 40.0 g of 4-hydroxybenzoic acid, 0.79 g of palladium acetate and 3.5 g of potassium acetate were charged into a separable flask of the same type as used in Reference Example 3 and subjected to reaction at 50° C. for 6 hours, while replacing the flask inside atomosphere with a nitrogen gas. After completion of the reaction, the reaction mixture was washed successively with an aqueous 0.5N sodium carbonate solution and water, and then treated in th same manner as in Reference Example 3, whereby 4.8 g of vinyl 4-hydroxybenzoate having the following chemical formula was obtained (yield: 10%): ##STR5##

後処理

  1. customsubjected to reaction at 50° C. for 6 hours
  2. customAfter completion of the reaction
  3. washthe reaction mixture was washed successively with an aqueous 0.5N sodium carbonate solution and water
  4. additiontreated in th same manner as in Reference Example 3, whereby 4.8 g of vinyl 4-hydroxybenzoate having the following chemical formula
  5. customwas obtained (yield: 10%)

出典と根拠

ORDレコード
ord-12e3692588a84529baaa0f3f0cbb473a
出典データセット
uspto-grants-1999_09
特許番号
US05959037

反応ノート

読み込み中…