Methyl 2-bromo-4-fluoro-5-nitrophenoxyformate → HCID 14370869、化合物
反応式
[F:1][C:2]1[CH:7]=[C:6]([Br:8])[C:5]([O:9][C:10]([O:12][CH3:13])=[O:11])=[CH:4][C:3]=1[N+:14]([O-])=O.[H][H]>[Pt](=O)=O.C(O)C>[F:1][C:2]1[CH:7]=[C:6]([Br:8])[C:5]([O:9][C:10]([O:12][CH3:13])=[O:11])=[CH:4][C:3]=1[NH2:14]参加物
5
実験手順
To an ethanol solution (300 ml) of 2-fluoro-4-bromo-5-methoxycarbonyloxy nitrobenzene (30.4 g, 0.1 mol) was added platinum dioxide (1.0 g) and the mixture was stirred under a hydrogen atmosphere until no hydrogen was absorbed. After the removal of the catalyst by filtration, the solvent of the filtrate was evaporated under reduced pressure to give a brown solid (28.0 g) of 2-fluoro-4-bromo-5-methoxycarbonyloxy aniline.
後処理
- customwas absorbed
- customAfter the removal of the catalyst
- filtrationby filtration
- customthe solvent of the filtrate was evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-75b4d53ac3b64a73922f7af49073a440
- 出典データセット
- uspto-grants-1989_04
- 特許番号
- US04818272
反応ノート
読み込み中…