Benzoyl Peroxide → 4-(Benzoxazol-2-yl)benzyl bromide

HRID 6210

反応式

HRID 6210 の反応式
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=3[N:12]=2)=[CH:4][CH:3]=1.[Br:17]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:17][CH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=3[N:12]=2)=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 700392-p-Tolylbenzoxazole

生成物 1

HCID 110335154-(Benzoxazol-2-yl)benzyl bromide

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒2 回

実験手順

A stirred solution of 20.9 g (0.1 mole) of 2-(4-methylphenyl)benzoxazole, 17.8 g (0.1 mole) of N-bromosuccinimide, and 0.4 g (0.2 mole %) of benzoyl peroxide in carbon tetrachloride is heated at reflux for 20 hours. After cooling to room temperature, the reaction is diluted by the addition of carbon tetrachloride, and the solid byproducts are removed by filtration. The filtrate is concentrated in vacuo, and the product is purified by recrystallization from benzene.

後処理

  1. temperatureat reflux for 20 hours
  2. customthe solid byproducts are removed by filtration
  3. concentrationThe filtrate is concentrated in vacuo
  4. customthe product is purified by recrystallization from benzene

出典と根拠

ORDレコード
ord-5c4084f677714fefb5da04262b23b483
出典データセット
uspto-grants-1993_09
特許番号
US05247042

関連ノート

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