Hydrogen Bromide → 8-hydroxy-3-methyl-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
反応式
Cl.[CH3:2][N:3]1[CH2:9][CH2:8][C:7]2[CH:10]=[C:11]([O:18]C)[C:12]([S:14]([CH3:17])(=[O:16])=[O:15])=[CH:13][C:6]=2[CH2:5][CH2:4]1.[BrH:20]>>[BrH:20].[OH:18][C:11]1[C:12]([S:14]([CH3:17])(=[O:16])=[O:15])=[CH:13][C:6]2[CH2:5][CH2:4][N:3]([CH3:2])[CH2:9][CH2:8][C:7]=2[CH:10]=1参加物
3
実験手順
Following the procedure of Example 4, 3-methyl-8-methoxy-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride was reacted with 48% hydrobromic acid to give 8-hydroxy-3-methyl-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, m.p. 310° (decomp.).
出典と根拠
- ORDレコード
- ord-1b77fe5cd83e44648db8809a9b90134d
- 出典データセット
- uspto-grants-1989_04
- 特許番号
- US04824839
反応ノート
読み込み中…