Acrylamide → 2-Vinyloxazoline-4,5-dione hydrochloride

HRID 622227

反応式

HRID 622227 の反応式
[C:1](Cl)(=[O:5])[C:2]([Cl:4])=[O:3].[C:7]([NH2:11])(=[O:10])[CH:8]=[CH2:9]>ClC(Cl)C>[ClH:4].[CH:8]([C:7]1[O:10][C:1](=[O:5])[C:2](=[O:3])[N:11]=1)=[CH2:9]

参加物

4

反応物 2

HCID 6579AcrylamideHCID 65578Oxalyl chloride

生成物 1

HCID 212839312-Vinyloxazoline-4,5-dione hydrochloride収率 99.7%

試薬・触媒・溶媒 1

HCID 63651,1-Dichloroethane溶媒

実験手順

Oxalyl chloride (130 g; 1.02 mol) was charged in a reactor, and a warm solution of acrylamide (71 g; 1.0 mol) in dichloroethane (250 ml) was dropwise added thereto (reaction temperature, 10° to 30° C.). After completion of the dropwise addition, the solvent and excess of the oxalyl chloride were removed by distillation under reduced pressure to obtain 2-vinyloxazoline-4,5-dione hydrochloride (161 g) as a yellow oil. Viscosity, 100,000 cp. Yield, 100%.

後処理

  1. custom(reaction temperature, 10° to 30° C.)
  2. additionAfter completion of the dropwise addition
  3. customthe solvent and excess of the oxalyl chloride were removed by distillation under reduced pressure

出典と根拠

ORDレコード
ord-101d2c0c76ac4f5f960392a377b50d8f
出典データセット
uspto-grants-1988_09
特許番号
US04769485

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