Pyridine → HCID 135617167、化合物
反応式
[NH2:1][C:2]1[N:3]([CH2:13][C:14]2[S:15][CH:16]=[CH:17][CH:18]=2)[C:4]2[N:5]=[C:6]([NH2:12])[NH:7][C:8](=[O:11])[C:9]=2[N:10]=1.CN([CH:22]=[O:23])C.N1C=CC=C[CH:25]=1.[C:30](OC(=O)C)(=[O:32])[CH3:31]>CCOCC>[O:11]=[C:8]1[NH:7][C:6]([NH:12][C:30](=[O:32])[CH3:31])=[N:5][C:4]2[N:3]([CH2:13][C:14]3[S:15][CH:16]=[CH:17][CH:18]=3)[C:2]([NH:1][C:22](=[O:23])[CH3:25])=[N:10][C:9]1=2参加物
6
実験手順
A mixture of 8-amino-9-[(2-thienyl)methyl]guanine (0.5 g; 1.88 mmol), DMF (10 ml), pyridine (5 ml), and acetic anhydride (5 ml) was stirred at room temperature for 36 hours. The mixture was diluted with ether (50 ml) and filtered to give analytically pure product, mp 243°-4° C.
後処理
- filtrationfiltered
- customto give analytically pure product, mp 243°-4° C.
出典と根拠
- ORDレコード
- ord-269cd4eedb054ca7af13eedc302ccae0
- 出典データセット
- uspto-grants-1988_09
- 特許番号
- US04772606
反応ノート
読み込み中…