2,2,2-Trifluoroethanol → Ethylaluminum Di-(2,2,2-trifluoroethoxide)

HRID 623181ノート

反応式

HRID 623181 の反応式
[F:1][C:2]([F:6])([F:5])[CH2:3][O-:4].[CH2:7]([Al+:9]CC)[CH3:8].[F:12][C:13]([F:17])([F:16])[CH2:14][OH:15].[Al]>>[F:1][C:2]([F:6])([F:5])[CH2:3][O-:4].[F:12][C:13]([F:17])([F:16])[CH2:14][O-:15].[CH2:7]([Al+2:9])[CH3:8]

参加物

4

反応物 3

HCID 64092,2,2-TrifluoroethanolHCID 5359268AluminumHCID 21290503Diethyl Aluminum 2,2,2-Trifluoroethoxide

生成物 1

HCID 21290501Ethylaluminum Di-(2,2,2-trifluoroethoxide)

反応条件

温度
55 °C

実験手順

In a flask were placed 10.27 g (55.75 mmoles) of the product of Example 1, under a nitrogen blanket. Then, 5.71 g (0.058 mole) of 2,2,2-trifluoroethanol was added dropwise. When the reaction mixture temperature reached 50° C., the flask was immersed in a chilled oil bath (0° C.) and the addition of fluoroalkanol was continued at a rate sufficient to maintain the temperature at 50°-55° C. After addition was completed, the reaction mixture was stirred for one hour at 55° C. The product was a viscous, colorless liquid. Analysis for aluminum showed 10.43% Al, which correlated well with the theoretical value of 10.58%.

後処理

  1. customIn a flask were placed
  2. customreached 50° C.
  3. customthe flask was immersed in a chilled oil bath
  4. temperatureto maintain the temperature at 50°-55° C
  5. additionAfter addition

出典と根拠

ORDレコード
ord-26461b03122d48d288daf73f932017d0
出典データセット
uspto-grants-1988_09
特許番号
US04774214

反応ノート

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