Oxalyl chloride → 1-Methyl-1,4-dihydro-2,3-quinoxalinedione
反応式
[C:1](Cl)(=[O:5])[C:2](Cl)=[O:3].[CH3:7][NH:8][C:9]1[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=1[NH2:11]>C(N(CC)CC)C.C1(C)C=CC=CC=1>[CH3:7][N:8]1[C:9]2[C:10](=[CH:12][CH:13]=[CH:14][CH:15]=2)[NH:11][C:2](=[O:3])[C:1]1=[O:5]参加物
5
実験手順
A mixture of 12 g of 98% oxalylchloride in 19.5 ml of triethylamine and 50 ml of toluene was added dropwise to a stirred solution of 8.5 g of o-N-methylamino aniline in 80 ml of toluene. The resulting mixture was heated at reflux for one hour. The precipitate was washed with ether. The residue was stirred with water and filtered to give 1,2,3,4-tetrahydro-1-methyl-2,3-dioxo-quinoxaline.
後処理
- temperatureThe resulting mixture was heated
- temperatureat reflux for one hour
- washThe precipitate was washed with ether
- filtrationfiltered
出典と根拠
- ORDレコード
- ord-b0fa077b0ee740b99315c72b14218da4
- 出典データセット
- uspto-grants-1988_09
- 特許番号
- US04774245
反応ノート
読み込み中…