Oxalyl chloride → 1-Methyl-1,4-dihydro-2,3-quinoxalinedione

HRID 623183

反応式

HRID 623183 の反応式
[C:1](Cl)(=[O:5])[C:2](Cl)=[O:3].[CH3:7][NH:8][C:9]1[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=1[NH2:11]>C(N(CC)CC)C.C1(C)C=CC=CC=1>[CH3:7][N:8]1[C:9]2[C:10](=[CH:12][CH:13]=[CH:14][CH:15]=2)[NH:11][C:2](=[O:3])[C:1]1=[O:5]

参加物

5

反応物 2

HCID 65578Oxalyl chlorideHCID 78498N-Methyl-o-phenylenediamine

生成物 1

HCID 6006271-Methyl-1,4-dihydro-2,3-quinoxalinedione

試薬・触媒・溶媒 2

HCID 1140Toluene溶媒2 回HCID 8471Triethylamine溶媒

実験手順

A mixture of 12 g of 98% oxalylchloride in 19.5 ml of triethylamine and 50 ml of toluene was added dropwise to a stirred solution of 8.5 g of o-N-methylamino aniline in 80 ml of toluene. The resulting mixture was heated at reflux for one hour. The precipitate was washed with ether. The residue was stirred with water and filtered to give 1,2,3,4-tetrahydro-1-methyl-2,3-dioxo-quinoxaline.

後処理

  1. temperatureThe resulting mixture was heated
  2. temperatureat reflux for one hour
  3. washThe precipitate was washed with ether
  4. filtrationfiltered

出典と根拠

ORDレコード
ord-b0fa077b0ee740b99315c72b14218da4
出典データセット
uspto-grants-1988_09
特許番号
US04774245

関連ノート

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