Hydrazine hydrate (1:1) → HCID 68750341、化合物

HRID 624157ノート

反応式

HRID 624157 の反応式
[NH2:1][C:2]1[CH:18]=[CH:17][C:5]([C:6]([C:8]2[CH2:13][CH2:12][CH2:11][CH2:10][C:9]=2[C:14](O)=[O:15])=O)=[CH:4][CH:3]=1.O.[NH2:20][NH2:21]>C(O)C>[NH2:1][C:2]1[CH:18]=[CH:17][C:5]([C:6]2[C:8]3[CH2:13][CH2:12][CH2:11][CH2:10][C:9]=3[C:14](=[O:15])[NH:21][N:20]=2)=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 68750696HCID 68750696、化合物

生成物 1

HCID 68750341HCID 68750341、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

10.3 g of 2-(4-amino-benzoyl)-cyclohex-1-enecarboxylic acid (42 mmol) were dissolved in 45 mL ethanol, 2.7 g (54 mmol) hydrazine hydrate was added and the mixture was heated under reflux for 30 hours. Precipitation of the product already started several hours after heating. After cooling in the refrigerator overnight the precipitated product was filtered and washed with cold ethanol.

後処理

  1. temperaturethe mixture was heated
  2. temperatureunder reflux for 30 hours
  3. customPrecipitation of the product already started several hours
  4. temperatureafter heating
  5. temperatureAfter cooling in the refrigerator overnight the precipitated product
  6. filtrationwas filtered
  7. washwashed with cold ethanol

出典と根拠

ORDレコード
ord-966dbe9931bb46c0835769b3c753dac0
出典データセット
uspto-grants-2016_04
特許番号
US09302989B2

反応ノート

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