Glucaric Acid → Adipic Acid

HRID 62568

反応式

HRID 62568 の反応式
[O:1]=[C:2]([OH:14])[C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([C:11]([OH:13])=[O:12])O)O)O)O.O=C(O)[C@@H]([C@H]([C@H]([C@@H](C(O)=O)O)O)O)O>[Re]>[C:11]([OH:13])(=[O:12])[CH2:9][CH2:7][CH2:5][CH2:3][C:2]([OH:14])=[O:1]

参加物

4

反応物 2

HCID 33037Glucaric AcidHCID 3037582Galactaric acid

生成物 1

HCID 196Adipic Acid

試薬・触媒・溶媒 1

HCID 23947Rhenium触媒

実験手順

Further, as described above, the starting material (glucaric acid or galactaric acid), rhenium catalyst, and acid catalyst are added to the reaction solvent, and reacted together at a proper temperature for a proper reaction time, then separated and purified with a conventional method (e.g., purification with silica column) to obtain glucaric acid ester or galactaric acid ester as an intermediate of adipic acid. In one embodiment, the reaction temperature ranges from 100 to 200° C., and the reaction time is 12 to 24 hours.

後処理

  1. additionare added to the reaction solvent
  2. customreacted together at a proper temperature for a proper reaction time
  3. customseparated
  4. custompurified with a conventional method (e.g., purification with silica column)

出典と根拠

ORDレコード
ord-e4d92eb81e1047428d952ffc9a9ab295
出典データセット
uspto-grants-2016_09
特許番号
US09447012B2

関連ノート

読み込み中…