6-Nitro-2,3-dihydrobenzofuran-5-amine → 2,3-Dihydrobenzofuran-5,6-diamine
反応式
[NH2:1][C:2]1[C:3]([N+:11]([O-])=O)=[CH:4][C:5]2[O:9][CH2:8][CH2:7][C:6]=2[CH:10]=1.[H][H]>CCO.[Pd]>[NH2:1][C:2]1[C:3]([NH2:11])=[CH:4][C:5]2[O:9][CH2:8][CH2:7][C:6]=2[CH:10]=1参加物
5
実験手順
The product obtained in Step 5 (2.5 g, 13.9 mmol) and Pd/C (0.5 g) were dissolved in EtOH (50 mL), hydrogenated in a Parr hydrogenation apparatus at room temperature and a hydrogen pressure of 50 PSI for 12 h. The catalyst was removed by filtration, the ethanol solution of the product was directly used in the next step of reaction.
後処理
- customThe catalyst was removed by filtration
- customthe ethanol solution of the product was directly used in the next step of reaction
出典と根拠
- ORDレコード
- ord-02a7d3eeb73a4c6fbc41806e5940cffe
- 出典データセット
- uspto-grants-2016_04
- 特許番号
- US09315513B2
反応ノート
読み込み中…