Toluene → 2-Methylbutyl 4-[p-(7-octenyloxy)benzoyloxy]biphenyl-4-carboxylate

HRID 6316

反応式

HRID 6316 の反応式
C1(C)C=CC=CC=1.O[C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([O:23][CH2:24][CH:25]([CH3:28])[CH2:26][CH3:27])=[O:22])=[CH:17][CH:16]=2)=[CH:11][CH:10]=1.[CH2:29]([O:37][C:38]1[CH:46]=[CH:45][C:41]([C:42]([OH:44])=[O:43])=[CH:40][CH:39]=1)[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH:35]=[CH2:36]>N1C=CC=CC=1>[CH2:29]([O:37][C:38]1[CH:39]=[CH:40][C:41]([C:42]([O:44][C:18]2([C:21]([O:23][CH2:24][CH:25]([CH3:28])[CH2:26][CH3:27])=[O:22])[CH:19]=[CH:20][C:15]([C:12]3[CH:13]=[CH:14][CH:9]=[CH:10][CH:11]=3)=[CH:16][CH2:17]2)=[O:43])=[CH:45][CH:46]=1)[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH:35]=[CH2:36]

参加物

5

反応物 3

HCID 1140TolueneHCID 139075372-Methylbutyl 4'-hydroxybiphenyl-4-carboxylateHCID 139976794-(7-Octenyloxy)benzoic acid

生成物 1

HCID 675687822-Methylbutyl 4-[p-(7-octenyloxy)benzoyloxy]biphenyl-4-carboxylate収率 45%

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

A toluene solution containing 10 g of 2-methylbutyl 4'-hydroxybiphenyl-4-carboxylate and 3 g of pyridine was added dropwise to the above-described toluene solution of the acid chloride compound. After conclusion of dropping, the temperature was raised, and reaction was carried out for 8 hours at 50° C. After conclusion of the reaction, the product was washed with water and dried over magnesium sulfate, and the dried product was concentrated under reduced pressure. The residue was recrystallized from ethanol to obtain 8.2 g of the objective ester compound. (Yield: 45%)

後処理

  1. temperaturethe temperature was raised
  2. customreaction
  3. customAfter conclusion of the reaction
  4. washthe product was washed with water
  5. dry with materialdried over magnesium sulfate
  6. concentrationthe dried product was concentrated under reduced pressure
  7. customThe residue was recrystallized from ethanol

出典と根拠

ORDレコード
ord-16d4578764164207b3fbaf490dfbb2e2
出典データセット
uspto-grants-1993_09
特許番号
US05248446

関連ノート

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