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tert-Butyl 3-(methylcarbamoyl)pentan-3-ylcarbamate → 2-Amino-2-ethyl-N-methyl-butyramide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-Butyl 3-(methylcarbamoyl)pentan-3-ylcarbamate | HCID 86674754 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | 2-Amino-2-ethyl-N-methyl-butyramide | HCID 79810370 | 75% |
反応手順
A mixture of tert-butyl 3-(methylcarbamoyl)pentan-3-ylcarbamate (0.18 g, 0.74 mmol) in 10 ml saturated hydrochloride in ethyl acetate was stirred for 60 min at room temperature. Then the solution was evaporated to dryness to obtain the product (80 mg, 75%) as a light yellow solid; MS (LC/MS): 145.2 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09321727B2 |
| 出典データセット | uspto-grants-2016_04 |
| ORD ID | ord-c87266b78f9b4f709056706310a5c905 |
| 出典メモ | uspto-grants-2016_04 |