Acetonitrile → 3-(6-(Cycloheptyloxy)pyridin-2-yl)-3-oxopropanenitrile
反応式
[CH:1]1([O:8][C:9]2[N:14]=[C:13]([C:15]([O:17]C)=O)[CH:12]=[CH:11][CH:10]=2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:19][C:20]#[N:21]>>[CH:1]1([O:8][C:9]2[N:14]=[C:13]([C:15](=[O:17])[CH2:19][C:20]#[N:21])[CH:12]=[CH:11][CH:10]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1参加物
3
実験手順
CH3CN addition to methyl 6-(cycloheptyloxy)picolinate following the method described in Example 6 gave 3-(6-(cycloheptyloxy)pyridin-2-yl)-3-oxopropanenitrile as a yellow oil which was used in the next step without further purification. Yield (1.29 g, quant.).
出典と根拠
- ORDレコード
- ord-3d6fee8f8d0d47a6a1166ee2fe3b8b62
- 出典データセット
- uspto-grants-2016_09
- 特許番号
- US09447078B2
反応ノート
読み込み中…