Hydrogen Bromide → 2-Bromo-1-(6-methylpyridin-3-yl)ethanone hydrobromide

HRID 633747

反応式

HRID 633747 の反応式
[CH3:1][C:2]1[N:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[CH:4][CH:3]=1.[BrH:11].BrBr>C(O)(=O)C>[BrH:11].[Br:11][CH2:9][C:8]([C:5]1[CH:6]=[N:7][C:2]([CH3:1])=[CH:3][CH:4]=1)=[O:10]

参加物

5

反応物 3

HCID 260Hydrogen BromideHCID 24408BromineHCID 952923-Acetyl-6-methylpyridine

生成物 1

HCID 454805112-Bromo-1-(6-methylpyridin-3-yl)ethanone hydrobromide

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

500 mg (3.59 mmol) of 1-(6-methylpyrid-3-yl)ethanone, 590 μl (3.59 mmol) of hydrobromic acid, 204 μl (3.95 mmol) of bromine and 10 mL of glacial acetic acid were used in the reaction. After precipitation with ethyl ether and filtration, 1.02 g of 2-bromo-1-(6-methylpyrid-3-yl)ethanone hydrobromide are obtained, the characteristics of which are as follows:

後処理

  1. customAfter precipitation
  2. filtrationwith ethyl ether and filtration, 1.02 g of 2-bromo-1-(6-methylpyrid-3-yl)ethanone hydrobromide
  3. customare obtained

出典と根拠

ORDレコード
ord-eee58b6607064dc58e5a858551127640
出典データセット
uspto-grants-2016_04
特許番号
US09321790B2

関連ノート

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