Thionyl Chloride → Benzylthiocarbonyl chloride

HRID 635016

反応式

HRID 635016 の反応式
[C:1]1([CH2:7][C:8](O)=[S:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:13])=O>>[C:1]1([CH2:7][C:8]([Cl:13])=[S:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 178526157HCID 178526157、化合物

生成物 1

HCID 19906501Benzylthiocarbonyl chloride収率 92%

反応条件

温度
40 °C

実験手順

A quantity of 762 g (4.536 mol) of 2-phenylthioacetic acid is stirred at room temperature for 3 hours with thionyl chloride (375 ml, 5.14 mol), then stirred at 40° C. for 3 hours. Rotary evaporation followed by bulb-to-bulb distillation gives 777 g (4.166 mol, 92%) of 2-phenylthioacetyl chloride.

後処理

  1. customRotary evaporation
  2. distillationfollowed by bulb-to-bulb distillation

出典と根拠

ORDレコード
ord-0760fb33a1f3464893b600b1f5082067
出典データセット
uspto-grants-2001_02
特許番号
US06184540B2

関連ノート

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