N-(oxan-4-ylidene)hydroxylamine → 3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-6,7-dihydro-4H-pyrano[4,3-c]isoxazole
反応式
[O:1]1[CH2:6][CH2:5][C:4](=[N:7][OH:8])[CH2:3][CH2:2]1.[F:9][C:10]1[CH:15]=[CH:14][C:13]([N:16]2[CH2:21][CH2:20][N:19]([CH2:22][CH2:23][CH2:24][C:25](OCC)=O)[CH2:18][CH2:17]2)=[CH:12][CH:11]=1>>[F:9][C:10]1[CH:11]=[CH:12][C:13]([N:16]2[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][CH2:24][C:25]3[O:8][N:7]=[C:4]4[CH2:3][CH2:2][O:1][CH2:6][C:5]=34)[CH2:20][CH2:21]2)=[CH:14][CH:15]=1参加物
3
実験手順
By the same reaction and treatment as in Example 48 using tetrahydro-4H-pyran-4-one oxime and ethyl 4-(4-(4-fluorophenyl)piperazin-1-yl)-n-butyrate, 3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-6,7-dihydro-4H-pyrano[4,3-c]isoxazole is obtained.
出典と根拠
- ORDレコード
- ord-1e4743d0791249f28f4d40409e991df5
- 出典データセット
- uspto-grants-2001_02
- 特許番号