Lithium, 1H-inden-1-yl- → N-tert-butyl-N-dimethylsilyl-1H-inden-1-amine
反応式
[CH-:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[Li+].[CH3:11][SiH:12]([N:14](Cl)[C:15]([CH3:18])([CH3:17])[CH3:16])[CH3:13]>C1COCC1>[CH3:11][SiH:12]([N:14]([CH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1)[C:15]([CH3:18])([CH3:17])[CH3:16])[CH3:13]参加物
4
実験手順
Lithium indenide (1.73 g, 0.014 moles) in THF (50 mL) was added drop wise to a solution of dimethylsilyl(t-butylamino)chloride (3.53 g, 0.021 moles) in THF (75 mL). This mixture was allowed to stir for 6.5 hrs. And the volatile materials were removed. The residue was extracted and filtered using hexane. Removal of the hexane resulted in the isolation of the desired product as an oil (2.53 g, 74.3% yield).
後処理
- customAnd the volatile materials were removed
- extractionThe residue was extracted
- filtrationfiltered
- customRemoval of the hexane
出典と根拠
- ORDレコード
- ord-4abf620f91d843c1b7c926a256f1cabb
- 出典データセット
- uspto-grants-2001_02
- 特許番号
- US06191245B1
反応ノート
読み込み中…