5-Methylimidazo[2,1-b]benzothiazole-2-methanol → HCID 11378925、化合物
反応式
[CH3:1][C:2]1[C:7]2[N:8]3[CH:13]=[C:12]([CH2:14][OH:15])[N:11]=[C:9]3[S:10][C:6]=2[CH:5]=[CH:4][CH:3]=1>C(Cl)Cl.CN(C=O)C.O=[Mn]=O>[CH:14]([C:12]1[N:11]=[C:9]2[N:8]([CH:13]=1)[C:7]1[C:2]([CH3:1])=[CH:3][CH:4]=[CH:5][C:6]=1[S:10]2)=[O:15]参加物
4
実験手順
2-Formyl-5-methylimidazo[2,1-b]-benzthiazole was prepared according to the procedure outlined in Example 1, (Step 3). Starting from 5-methyl imidazo[2,1-b]-benzthiazole-2-methanol (2.0 g 9.1 mmol) in methylene chloride/DMF (300 mL: 50 mL) and active MnO2 (12 g, excess), 700 mg (35% Yield) of the aldehyde derivative was isolated as brown solid. (M+H) 217.
後処理
- customwas isolated as brown solid
出典と根拠
- ORDレコード
- ord-c4b174ffa806400aaa293a2381e95866
- 出典データセット
- uspto-grants-2010_04
- 特許番号
- US07691842B2
反応ノート
読み込み中…