Methyl iodide → HCID 68683485、化合物

反応式

[CH3:1][O:2][C:3](=[O:16])[C:4]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([OH:12])=[C:6]([CH2:13][CH:14]=[CH2:15])[CH:5]=1.[CH3:17]I>>[CH3:1][O:2][C:3](=[O:16])[C:4]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:17])=[C:6]([CH2:13][CH:14]=[CH2:15])[CH:5]=1

参加物

反応物 2

HCID 6328Methyl iodide

HCID 7131942methyl 3-allyl-4-hydroxy-5-methoxybenzoate

生成物 1

HCID 68683485HCID 68683485、化合物収率 96%

実験手順

3-Allyl-4,5-dimethoxybenzoic acid methyl ester was prepared from 3-allyl-4-hydroxy-5-methoxybenzoic acid methyl ester (Example 1, Step 2) by following Method C using methyl iodide as alkylating agent. The reaction was conducted at room temperature for 16 h and crude product was purified by flash column chromatography (96% yield).

後処理

customcrude product was purified by flash column chromatography (96% yield)

出典と根拠

ORDレコード: ord-ecbe9b079b2447e4a1c9cd9d8e58b046
出典データセット: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07691843B2

反応ノート

読み込み中…