1,3-Dibromo-5,5-dimethylhydantoin → 1-Bromo-3,5-dinitrobenzene
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([N+:10]([O-:12])=[O:11])[CH:5]=1)([O-:3])=[O:2].[Br:13]N1C(C)(C)C(=O)N(Br)C1=O>S(=O)(=O)(O)O>[Br:13][C:8]1[CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=[C:6]([N+:10]([O-:12])=[O:11])[CH:7]=1参加物
4
実験手順
To a solution of 1,3-dinitrobenzene (25 g, 0.149 mol) in concentrated sulfuric acid (100 ml) at 0° C. was added 1,3-dibromo-5,5-dimethylhydantoin (31.75 g, 0.111 mol, 0.75 eq) portionwise over a period of 30 min. The mixture was stirred for 12 at RT and quenched by the addition of crushed ice. The precipitate formed was filtered and was washed repeatedly with water to obtain white solid. The solid was dried under vacuum to give the product in 87% yield (32 g).
後処理
- customquenched by the addition of crushed ice
- customThe precipitate formed
- filtrationwas filtered
- washwas washed repeatedly with water
- customto obtain white solid
- customThe solid was dried under vacuum
- customto give the product in 87% yield (32 g)
出典と根拠
- ORDレコード
- ord-f1f8d9b2cac248a29d37c63b1939fb42
- 出典データセット
- uspto-grants-2016_09
- 特許番号
- US09447091B2
反応ノート
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