Thionyl Chloride → 3-(1-Cyanoethyl)benzoyl chloride
反応式
[C:1]([CH:3]([C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8](O)=[O:9])[CH3:4])#[N:2].S(Cl)([Cl:16])=O>>[C:1]([CH:3]([C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8]([Cl:16])=[O:9])[CH3:4])#[N:2]参加物
3
反応条件
- 温度
- 80 °C
実験手順
Thionyl chloride (10 mL) was added at 0° C. to 3-(l-cyanoethyl)benzoic acid (12, 500 mg, 2.85 mmol). The reaction mixture was heated at 80° C. for 2 h. The excess thionyl chloride was removed to give 3-(l-cyanoethyl)benzoyl chloride, which was used without further purification.
後処理
- customThe excess thionyl chloride was removed
出典と根拠
- ORDレコード
- ord-8877b751d591410e9acb89acc69b4fd4
- 出典データセット
- uspto-grants-2016_09
- 特許番号
- US09447134B2
反応ノート
読み込み中…