Ethyl indole-2-carboxylate → 1-Benzofuran-3-ylmethyl-1H-indole-2-carboxylic acid
反応式
C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:5])C.Br[CH2:16][C:17]1[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[O:19][CH:18]=1>>[O:19]1[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[C:17]([CH2:16][N:7]2[C:8]3[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:14]=[C:6]2[C:4]([OH:3])=[O:5])=[CH:18]1参加物
3
実験手順
Using general procedure B, 1H-indole-2-carboxylic acid ethyl ester was coupled with 3-bromomethyl-benzofuran (Lit. 19) and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 290.2 ([M−H]−).
後処理
- customthe product obtained
出典と根拠
- ORDレコード
- ord-947feb824466429bbd46cde81b879ea7
- 出典データセット
- uspto-grants-2010_04
- 特許番号
- US07696240B2
反応ノート
読み込み中…