HCID 11713695、化合物 → HCID 11583416、化合物
反応式
C([O:8][C:9]1[CH:41]=[CH:40][C:12]2[C:13]3[N:14]([CH2:25][C:26]4[CH:39]=[CH:38][C:29]([O:30][CH2:31][CH2:32][N:33]([CH2:36][CH3:37])[CH2:34][CH3:35])=[CH:28][CH:27]=4)[C:15]4[CH:16]=[CH:17][C:18]([O:23][CH3:24])=[CH:19][C:20]=4[C:21]=3[O:22][C:11]=2[CH:10]=1)C1C=CC=CC=1>CCO.[Pd]>[CH2:36]([N:33]([CH2:34][CH3:35])[CH2:32][CH2:31][O:30][C:29]1[CH:38]=[CH:39][C:26]([CH2:25][N:14]2[C:15]3[CH:16]=[CH:17][C:18]([O:23][CH3:24])=[CH:19][C:20]=3[C:21]3[O:22][C:11]4[CH:10]=[C:9]([OH:8])[CH:41]=[CH:40][C:12]=4[C:13]2=3)=[CH:27][CH:28]=1)[CH3:37]参加物
4
反応条件
- 温度
- 25 °C
実験手順
A mixture of {2-[4-(7-benzyloxy-3-methoxy-benzo[4,5]furo[3,2-b]indol-10-ylmethyl)-phenoxy]-ethyl}-diethyl-amine (102 mg, 0.186 mmol) and 10% Pd/C (˜100 mg) in EtOH (10 mL) was stirred under a H2 balloon at 25° C. overnight. The solution was filtered, concentrated and purified to yield the title compound as a yellow solid.