Thionyl Chloride → 6,6-Difluorohex-5-enoic acid chloride
反応式
S(Cl)([Cl:3])=O.[F:5][C:6]([F:14])=[CH:7][CH2:8][CH2:9][CH2:10][C:11](O)=[O:12]>CN(C)C=O>[F:5][C:6]([F:14])=[CH:7][CH2:8][CH2:9][CH2:10][C:11]([Cl:3])=[O:12]参加物
4
実験手順
10.23 ml (140.68 mmol) Thionyl chloride was added dropwise to 8.0 g (52.29 mmol) of the product of Example 9 at room temperature. A drop of dimethylformamide was added and the mixture heated under reflux for 6 hours. It was then distilled under reduced pressure.
後処理
- temperaturethe mixture heated
- temperatureunder reflux for 6 hours
- distillationIt was then distilled under reduced pressure
出典と根拠
- ORDレコード
- ord-d30cf53005b044ea9db9fca6b67dce41
- 出典データセット
- uspto-grants-1993_09
- 特許番号
- US05248810
反応ノート
読み込み中…