[N:1]1([CH2:7][C:8]2[CH:9]=[C:10]([CH:31]=[CH:32][CH:33]=2)[O:11][CH2:12][CH2:13][CH2:14][NH:15][C:16]2[CH:21]=[C:20]([O:22]CC3C=CC=CC=3)[CH:19]=[CH:18][N+:17]=2[O-:30])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(O)(C)C.C(O)(C)C.CC(C)=O>C(O)C.[Pd]>[N:1]1([CH2:7][C:8]2[CH:9]=[C:10]([CH:31]=[CH:32][CH:33]=2)[O:11][CH2:12][CH2:13][CH2:14][NH:15][C:16]2[CH:21]=[C:20]([OH:22])[CH:19]=[CH:18][N+:17]=2[O-:30])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]12-[3-[3-(Piperidinomethyl)phenoxy]propylamino]-4-benzyloxypyridine-N-oxide (0.94 g) in ethanol (100 ml) was hydrogenated at 344 KPa (50 p.s.i.), for 5 hours in the presence of 10% palladium on charcoal (0.1 g). The reaction mixture was filtered and the filtrate evaporated under reduced pressure to give an oil. Trituration under diethyl ether containing a little isopropanol gave as a buff solid 2-[3-[3-(piperidinomethyl)phenoxy]propylamino]-4-hydroxypyridine-N-oxide (0.59 g), m.p. 140°-142.5° C. (recrystallised from isopropanol-acetone).
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