p-Toluenesulfonic acid → Isobutyl-4-(Propylthio)Butyrate

HRID 649351

反応式

HRID 649351 の反応式
[CH3:1][O:2][C:3](=[O:11])[CH2:4][CH2:5][CH2:6][S:7][CH2:8][CH2:9][CH3:10].[CH2:12](O)[CH:13](C)[CH3:14].C1(C)C=CC(S(O)(=O)=O)=CC=1>>[CH2:1]([O:2][C:3](=[O:11])[CH2:4][CH2:5][CH2:6][S:7][CH2:8][CH2:9][CH3:10])[CH:13]([CH3:14])[CH3:12]

参加物

4

反応物 3

HCID 6101p-Toluenesulfonic acidHCID 6560IsobutanolHCID 20143889Methyl-4-(Propylthio)Butyrate

生成物 1

HCID 20143891Isobutyl-4-(Propylthio)Butyrate

実験手順

Into a 25 mm micro flask equipped with spin bar, hot plate (having built in magnetic stirrer), reflux condenser and thermometer are placed 5 grams (0.0284 moles) of methyl-4-(propylthio)butyrate; 8.4 grams (0.1136 moles) of isobutanol and 0.05 grams of para-toluene sulfonic acid. The reaction mass is heated to reflux and maintained at reflux with stirring for a period of 14.5 hours. At the end of the refluxing, the reaction mass is cooled and distilled on a micro Vigreux column yielding the following fractions:

後処理

  1. customInto a 25 mm micro flask equipped with spin bar
  2. temperaturehot plate (having built in magnetic stirrer), reflux condenser
  3. temperatureThe reaction mass is heated
  4. temperatureto reflux
  5. temperaturemaintained
  6. temperatureat reflux
  7. temperatureAt the end of the refluxing, the reaction mass is cooled
  8. distillationdistilled on a micro Vigreux column
  9. customyielding the following fractions

出典と根拠

ORDレコード
ord-890cc47db4dc40c9b782c98ba057f760
出典データセット
uspto-grants-1988_04
特許番号
US04739105

関連ノート

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