Benzo(B)Thiophene → 2,3-Dihydrobenzo(b)thiophene
反応式
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[CH:2]1>O.[Na].[Hg]>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH2:3][CH2:2]1参加物
4
実験手順
The dihydrobenzothiophenes are prepared as depicted in Chart D. A solution of a formula LX benzothiophene in water is stirred with excess sodium amalgam (NaHg) for 24 hr. After workup there is obtained the corresponding Formula LXI dihydrobenzothiophene. (See, e.g., D. T. Witiak, et al., J. Med. Chem. 14, 754 (1971).)
出典と根拠
- ORDレコード
- ord-b72bcf250541411db5b39c9ed0780759
- 出典データセット
- uspto-grants-1986_09
- 特許番号
- US04611059
反応ノート
読み込み中…